David Greg Fitzharris, PhD
Professeur titulaire
Lieu de pratique
CRCHUM, Tour Viger
Formation
- Baccalauréat, Physiologie et Pharmacologie, University College de Londres, Angleterre, 2000
- Ph.D. (Doctorat) : Physiologie, University College de Londres, Angleterre, 2004
- Postdoctorat, Ottawa Health Research Institute, 2007
Intérêts de recherche
- Mécanismes de conception d’ovules et d’embryons sains
- Compréhension de l’impact de l’âge maternel sur les ovules et embryons et effet sur la fertilité
- Microscopie de cellules vivantes
Projets en cours
- Understanding the role of motor proteins in age-related oocyte aneuploidy and infertility
- Understanding the causes and consequences of chromosome segregation errors in the early embryo
- Understanding the regulation of centriole giogenesis in the early embyo
Publications choisies
- Tsichlaki E, FitzHarris G. Nucleus downscaling in mouse embryos is regulated by cooperative developmental and geometric programs. Sci Rep. 2016 Jun 20;6:28040. doi: 10.1038/srep28040.
- Haverfield J, Nakagawa S, Love D, Tsichlaki E, Nomikos M, Lai FA, Swann K, FitzHarris G. Ca(2+) dynamics in oocytes from naturally-aged mice. Sci Rep. 2016 Jan 20;6:19357. doi: 10.1038/srep19357.
- Vázquez-Diez C, Yamagata K, Trivedi S, Haverfield J, FitzHarris G. Micronucleus formation causes perpetual unilateral chromosome inheritance in mouse embryos. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):626-31. doi: 10.1073/pnas.1517628112.
- Nakagawa S, FitzHarris G. Quantitative Microinjection of Morpholino Antisense Oligonucleotides into Mouse Oocytes to Examine Gene Function in Meiosis-I. Methods Mol Biol. 2016;1457:217-30. doi: 10.1007/978-1-4939-3795-0_16.